abstract：BACKGROUND:West Nile virus (WNV) infection is mostly asymptomatic (AS) but 20% of subjects report WNV fever and 1% of patients experience neurologic diseases with higher rates in elderly and immunosuppressed persons. With no treatment and no vaccine to prevent the development of symptomatic (S) infections, it is essent...

journal_title：Transfusion

authors： Kaidarova Z,Bravo MD,Kamel HT,Custer BS,Busch MP,Lanteri MC

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Mobilized peripheral blood is the most common source of CD34+ cells intended for transplantations. The collection and enrichment of CD34+ cells could be affected by various factors and there are some controversies regarding the effects of patient-related factors. The aim of this study was to assess the impac...

journal_title：Transfusion

authors： Kresnik PK,Krasna M,Rozman P,Vrtovec B,Malicev E

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Aprotinin has been reapproved for use in Europe and in Canada. We sought to determine if its reintroduction was still pertinent given the widespread administration of tranexamic acid, another antifibrinolytic shown to reduce bleeding and transfusions. STUDY DESIGN AND METHODS:After institutional review boar...

journal_title：Transfusion

authors： Stevens LM,Noiseux N,Prieto I,Hardy JF

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) infections in very-low-birthweight infants can lead to serious clinical consequences. When CMV-related symptoms occur after transfusion, CMV transmission is often attributed to the transfusion products rather than to breast milk. However, it is sometimes difficult to distinguish between...

journal_title：Transfusion

authors： Yamagishi N,Furui Y,Koshinami S,Ichijo K,Shimizu Y,Hoshi Y,Gotanda Y,Miyakawa K,Uchida S,Tadokoro K,Nagai T,Satake M

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Bartonella spp. are neglected fastidious Gram-negative bacilli. We isolated Bartonella henselae from 1.2% of 500 studied blood donors and demonstrated that the bacteria remain viable in red blood cell units after 35 days of experimental infection. Now, we aim to evaluate the possibility of B. henselae transm...

journal_title：Transfusion

authors： Silva MN,Vieira-Damiani G,Ericson ME,Gupta K,Gilioli R,de Almeida AR,Drummond MR,Lania BG,de Almeida Lins K,Soares TC,Velho PE

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Allogeneic transfusion can result in alloimmunization, leading to platelet (PLT) refractoriness and rejection of solid organ transplants. Previously we demonstrated that pathogen reduction using UV light and riboflavin (UV + R) eliminates the immunogenicity of white blood cells (WBCs) in vitro, blocks alloim...

journal_title：Transfusion

authors： Muench MO,Heitman JW,Inglis H,Fomin ME,Marschner S,Goodrich RP,Norris PJ,Jackman RP

更新日期：2016-06-01 00:00:00

abstract：:Transfusion-transmitted cytomegalovirus (TT-CMV) is often asymptomatic, but certain patient populations, such as very low birth weight neonates, fetuses requiring intrauterine transfusion, pregnant women, patients with primary immunodeficiencies, transplant recipients, and patients receiving chemotherapy or transplant...

journal_title：Transfusion

authors： AABB, Clinical Transfusion Medicine Committee.,Heddle NM,Boeckh M,Grossman B,Jacobson J,Kleinman S,Tobian AA,Webert K,Wong EC,Roback JD

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The Lu(b) antigen is expressed on red blood cells (RBCs) of the majority of individuals in all populations. Its absence in transfused patients may lead to alloantibody production and mild-to-moderate transfusion reactions, and in pregnancies to mild hemolytic disease of the fetus and newborn. This report des...

journal_title：Transfusion

authors： Garcia-Sanchez F,Pardi C,Kupatawintu P,Thornton N,Rodriguez MA,Lucea I,Sood C,Ochoa-Garay G

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization is a concern for patients who receive multiple or chronic transfusions. Alloimmunization prevalence in transfused patients with bone marrow failure syndrome (BMFS) is unknown. This study aimed to determine physician practice for RBC antigen matching, immunization rates, ...

journal_title：Transfusion

authors： Cohen D,Hartung H,Evans P,Friedman DF,Chou ST

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) storage lesions and RBCs from females transfused into male recipients may have adverse effects on transfusion recipients' survival. We hypothesized that the effect of donor sex and the effect of age of blood on mortality would be most apparent in cardiac surgery patients. STUDY DESIGN A...

journal_title：Transfusion

authors： Desmarets M,Bardiaux L,Benzenine E,Dussaucy A,Binda D,Tiberghien P,Quantin C,Monnet E

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Platelet concentrates (PCs) are the most common blood components eliciting nonhemolytic transfusion reactions (NHTRs), such as allergic transfusion reactions and febrile reactions. However, the precise mechanisms of NHTRs in PC transfusion remain largely unknown. Previous studies reported that mitochondria-d...

journal_title：Transfusion

authors： Yasui K,Matsuyama N,Kuroishi A,Tani Y,Furuta RA,Hirayama F

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Unexpected antibodies are frequently associated with hemolytic disease of the fetus and newborn (HDFN) and hemolytic transfusion reactions (HTRs), and screening for those unexpected antibodies is critical for the safety and effectiveness of transfusion. Different populations differ in the prevalence of signi...

journal_title：Transfusion

authors： Chen C,Tan J,Wang L,Han B,Sun W,Zhao L,Huang C,Tan B,Qin L

更新日期：2016-04-01 00:00:00

abstract：:The development of transfusion over the past century and a half has been described as one of the blessings of modern medicine. But, in some ways, it is emerging as a decidedly mixed blessing, bringing epidemics as well as improved health. Given all the practice has been through, now is the right time to take a critica...

journal_title：Transfusion

authors： Farrugia A,Starr D

更新日期：2016-04-01 00:00:00

abstract：:This review considers the various methods currently in use, or under investigation, for the storage of platelets intended for use in the treatment of active hemorrhage. The current standard practice of storing platelets at room temperature (RT) (20°C-24°C) optimizes circulating time, but at the expense of hemostatic f...

journal_title：Transfusion

authors： Milford EM,Reade MC

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:In 2009 the Mirasol Pathogen Reduction Technology (PRT) was introduced to the routine blood component production of the Regional Blood Transfusion Center in Warsaw (RBTCW). The goal of this study was to investigate the safety of Mirasol-treated blood components. STUDY DESIGN AND METHODS:The accumulated pass...

journal_title：Transfusion

authors： Łętowska M,Przybylska Z,Piotrowski D,Lachert E,Rosiek A,Rzymkiewicz L,Cardoso M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Intraoperative and postoperative red blood cell (RBC) transfusions are relatively frequent events tracked in the American College of Surgeons' National Surgical Quality Improvement Program-Pediatric (ACS-NSQIP-P). This study sought to quantify variation in RBC transfusion practices among hospitals. STUDY DE...

journal_title：Transfusion

authors： Stey AM,Vinocur CD,Moss RL,Hall BL,Cohen ME,Kraemer K,Ko CY,Kenney BD

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The effect on component wastage after enhancing the clinician's ability to order blood products in the computerized physician order entry (CPOE) system was investigated in a multihospital network. METHODS:A novel field was added to the CPOE of eight hospitals within a health care system allowing the physici...

journal_title：Transfusion

authors： Yazer MH,Deandrade DS,Triulzi DJ,Wisniewski MK,Waters JH

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:To meet European guidelines for plasma for fractionation, plasma fractionators have implemented parvovirus B19 (B19V) and hepatitis A virus (HAV) nucleic acid test (NAT) screening on test pools. In this study we evaluate recently developed in-house NAT assays for B19V DNA and HAV RNA. The B19V NAT was design...

journal_title：Transfusion

authors： Molenaar-de Backer MW,de Waal M,Sjerps MC,Koppelman MH

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:New alloantibody formation is unpredictable in patients who have been previously alloimmunized. Pretransfusion testing is designed to detect these antibodies while antibody identification (ABI) techniques are designed to identify the specificity of the antibody. Pretransfusion testing intervals are prescribe...

journal_title：Transfusion

authors： Goss C,Avecilla ST,Garbaini J,Degtyaryova D,Lo D,Chang DY,Cushing M

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:During storage, the activity of the red blood cell (RBC) antioxidant system decreases. Glucose-6-phosphate dehydrogenase (G6PD) is essential for protection against oxidative stress by producing NADPH. G6PD function of RBC transfusion products is reported to remain stable during storage, but activity was meas...

journal_title：Transfusion

authors： Peters AL,van Bruggen R,de Korte D,Van Noorden CJ,Vlaar AP

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Tranexamic acid (TXA) has been reported to demonstrate efficacy in reducing blood loss during arthroplasty procedures. STUDY DESIGN AND METHODS:This study examines the effectiveness of TXA as a central element of a patient blood management program (PBMP) by evaluating blood loss and transfusion of red blood...

journal_title：Transfusion

authors： Pitta M,Zawadsky M,Verstraete R,Rubinstein A

更新日期：2016-02-01 00:00:00

abstract：:Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable. HTLV screening of blood donations became mandatory in different countries to improve the safety of blood suppl...

journal_title：Transfusion

authors： Marano G,Vaglio S,Pupella S,Facco G,Catalano L,Piccinini V,Liumbruno GM,Grazzini G

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Blood has been imbued with powerful connotations through history and across cultures. Currently bestowed with scientific meaning, blood nevertheless carries symbolic resonance. This study examines these representations among practitioners and sheds light on the clinical and nonclinical factors that guide blo...

journal_title：Transfusion

authors： Fortin S,Cardona LG,Latreille M,Tucci M,Lacroix J

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) transfusion is the primary treatment for thrombocytopenia. PLTs are obtained exclusively from volunteer donors, and the PLT product has only a 5-day shelf life, which can limit supply and result in PLT shortages. PLTs derived from stem cells could help to fill this clinical need. However, curr...

journal_title：Transfusion

authors： Avanzi MP,Oluwadara OE,Cushing MM,Mitchell ML,Fischer S,Mitchell WB

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Screening of blood donors for antibody to human immunodeficiency virus Types 1 and 2 (anti-HIV-1/2) and/or HIV nucleic acid test (NAT) is a well-established venue to prevent HIV transfusion-transmitted disease. However, with the current available technologies, HIV testing may result in donor loss due to fals...

journal_title：Transfusion

authors： Li L,Xu T,Yang T,Zang L,Cheng W,Lin H,Zhu S,Zhao B,Duan R,Li C,Huang M,Liu Y,Ming C,Xu S,Wang C,Wu Y,Liu Z

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Maternal iron deficiency anemia (IDA) impacts placenta and fetus. We evaluated effects of IDA at admission for delivery on cesarean rates, and adverse maternal and neonatal outcomes. STUDY DESIGN AND METHODS:Medical records from Jerusalem (2005-2012) identified women with a live-birth singleton fetus in cep...

journal_title：Transfusion

authors： Drukker L,Hants Y,Farkash R,Ruchlemer R,Samueloff A,Grisaru-Granovsky S

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Recent genome-wide association studies in Caucasians suggested that an association exists between the ABO gene locus and soluble levels of P-selectin (sP-selectin). However, it is unclear if the relationship corresponds to the phenotypic expression of ABO groups or is present in different ethnic groups. The ...

journal_title：Transfusion

authors： Chen Y,Zhuo X,Lin Y,Huang W,Xiao J,Zeng J,Jiang L,Chen C,Lin H,Dettke M

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:When problems with compatibility beyond ABO and D arise, currently transfusion services search their inventories and perform time-consuming serologic testing to locate antigen-negative blood. These clinically important blood group antigens can be detected reliably by red cell genotyping, which is a technolog...

journal_title：Transfusion

authors： Flegel WA,Gottschall JL,Denomme GA

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Plasma is commonly used for vitamin K antagonist (VKA) reversal, but observational studies suggest that it is associated with transfusion-related adverse reactions (e.g., volume overload). However, this issue has not previously been addressed in a randomized controlled trial (RCT). STUDY DESIGN AND METHODS:...

journal_title：Transfusion

authors： Refaai MA,Goldstein JN,Lee ML,Durn BL,Milling TJ Jr,Sarode R

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Transfusion support of S-s- patients is very challenging but can now be alleviated by genotyping mutations in the GYPB gene to predict their U- or U+(var) phenotype. However, the phenotype predicted by genotyping does not always correspond to the observed phenotype of red blood cells (RBCs), which requires f...

journal_title：Transfusion

authors： Willemetz A,Nataf J,Peyrard T,Arnaud L

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) antigen and antibody combination assays have been launched as a cost-effective alternative to nucleic acid testing (NAT) for reducing the antibody-negative window period (WP). Later, a HCV antigen chemiluminescence immunoassay (CLIA) became available. STUDY DESIGN AND METHODS:A panel...

journal_title：Transfusion

authors： Laperche S,Nübling CM,Stramer SL,Brojer E,Grabarczyk P,Yoshizawa H,Kalibatas V,El Elkyabi M,Moftah F,Girault A,van Drimmelen H,Busch MP,Lelie N

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a severe disorder affecting the microcirculation of multiple organs due to a systemic endothelial cell injury secondary to a deficiency in ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13) activity. TTP is a rare complication...

journal_title：Transfusion

authors： Gasparri ML,Bellati F,Brunelli R,Perrone G,Pecorini F,Papadia A,Meloni G,Trisolini SM,Gozzer M,Domenici L,Lecce F,Benedetti Panici P

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:This multicenter study was performed to evaluate the efficiency of a multiplex individual-donation nucleic acid amplification technology (ID-NAT) and discriminatory testing algorithm for detecting hepatitis B virus (HBV) infection in Chinese blood donors. STUDY DESIGN AND METHODS:A total of 1,205,796 hepati...

journal_title：Transfusion

authors： Gou H,Pan Y,Ge H,Zheng Y,Wu Y,Zeng J,Yang Z,Pan T,Cun W,Zhou G,Fang G,Zhang J,Zhang K,Zhang R,Sun Y,Xie J,Li J,Wang L

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Pulmonary transfusion reactions are important complications of blood transfusion, yet differentiating these clinical syndromes is diagnostically challenging. We hypothesized that biologic markers of inflammation could be used in conjunction with clinical predictors to distinguish transfusion-related acute lu...

journal_title：Transfusion

authors： Roubinian NH,Looney MR,Kor DJ,Lowell CA,Gajic O,Hubmayr RD,Gropper MA,Koenigsberg M,Wilson GA,Matthay MA,Toy P,Murphy EL,TRALI Study Group.

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Successful hematopoietic stem cell transplantation using stored umbilical cord blood (CB) largely depends on cell dose and quality of CB units. The aim of this study was to assess the degree of early apoptosis, in addition to cell viability and hematopoietic potential, in umbilical CB units after storage. S...

journal_title：Transfusion

authors： Kim KM,Huh JY,Hong SS,Kang MS

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Blood-borne infections remain a risk of blood transfusions. While routine screening of donated blood products has greatly reduced the risk of human immunodeficiency virus, hepatitis B, and hepatitis C transmission, arboviruses such as dengue, chikungunya, and the West Nile virus remain significant risks espe...

journal_title：Transfusion

authors： Oh HB,Muthu V,Daruwalla ZJ,Lee SY,Koay ES,Tambyah PA

更新日期：2015-07-01 00:00:00

abstract：:Intravenous immune globulin (IVIG) therapy has shown great success in a number of autoimmune and inflammatory conditions and its use continues to increase worldwide. There is growing awareness of significant side effects of high-dose IVIG: however, particularly severe hemolysis in patients that are non-group O. It has...

journal_title：Transfusion

authors： Pendergrast J,Willie-Ramharack K,Sampson L,Laroche V,Branch DR

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The formation of red blood cell (RBC) antibodies could be enhanced by the presence of inflammation caused by prolonged RBC storage, as was shown in animal studies. The low occurrence (<10%) of K-antigen in most populations often enables identification of the K+ RBC unit that triggered anti-K formation and de...

journal_title：Transfusion

authors： Hogervorst E,Middelburg R,Brand A,van de Watering L,Schonewille H

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Recent retrospective studies indicate that D- recipients of D+ apheresis platelets (PLTs) are not alloimmunized to D. Our hospital policy is to offer RhIG to D- women of childbearing age who received D+ apheresis PLTs but not to other D- recipients of D+ apheresis PLTs. We instituted prospective surveillance...

journal_title：Transfusion

authors： Weinstein R,Simard A,Ferschke J,Vauthrin M,Bailey JA,Greene M

更新日期：2015-06-01 00:00:00